MOLECULAR TEST
Medical Lab Expert - Microbiological Laboratory | Ilion Attica

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In molecular testing, tests are performed to detect the genetic material of microbes (Molecular Microbiology) as well as tests to detect and identify mutations related to hereditary diseases.
Also included in the molecular test are many tests related to prenatal control, neoplastic disease control, STDs (sexually transmitted diseases), etc.

Indicative molecular testing for Thrombophilia:
FACTOR V G1691A FV Leiden
FACTOR II-Prothrombin G20210A
MTHFR- C677T
MTHFR- A1298C
Control of the 12 FACTOR V G1691A FV Leiden mutations
FACTOR II-Prothrombin, G20210A, MTHFR-C677T, MTHFR- A1298C, FV 1299, PAI 5G/4G, FXIII, FV CAMBRIDGE, Beta Fib, FV 1702, MTR 2756, MTRR 66

Cystic fibrosis 18 mutations (∆F508, G542X, W1282X, E92K, 1677delTA, K68E, 2789+5G>A, 1717-1G>A, 4010delTATT, F1052V, I148T, G551D, Y1032C, 3849+10kbC>T, R560 T,2183AAG, S4X, N1303K).
of the entire CFTR gene (all 24 exons, including deletions) by Next Generation Sequencing (NGS), covering >99% of disease mutations.

SMN Spinal Muscular Atrophy Control
Spinal Muscular Atrophy comprises a group of neuromuscular disorders characterized by degeneration of the anterior horns of α-motor neurons of the spinal cord resulting in symmetrical muscle weakness and motor muscle degeneration.
Four subtypes have been defined according to age of onset and disease severity: Type 1 (SMA1), the most severe form, with onset before six months of age. Type 2 (SMA2), with onset between 6 and 18 months of age. Type 3 (SMA3), with onset during childhood and adolescence, and Type 4 (SMA4), the less severe form, with onset in adulthood.

HLA B27
Human Leukocyte Antigen (HLA) antigens are present on the surface of white blood cells as well as on the surface of all nucleated cells. The presence or absence of these antigens is genetically determined. HLA-B27 is found in 90% of patients with ankylosing spondylitis and 80% of patients with Reiter's syndrome (reactive arthritis).